Exosome extraction device and exosome extraction method
US12109517B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 9, 2021 |
| Grant date | Oct 8, 2024 |
| Priority date | — |
| Expiry date | Aug 20, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2311/2692
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A liquid containing exosomes is filtered through a first filter that has a hole diameter that passes the exosomes and blocks cells, and is then stored in a first storage unit (rough filtration step). Next, pressure is applied to the inside of the first storage unit to pump the liquid to a pre-filtration chamber in a second filter that blocks the exosomes so that water in the liquid is filtered out into a post-filtration chamber. The exosome-containing liquid that was not filtered out is returned to the first storage unit, thereby increasing the exosome concentration in the liquid for extraction (concentration step). The exosome-containing concentrate in the first storage unit is then filtered through a third filter having a hole diameter that passes the exosomes and blocks bacteria, and is sent to a recovery unit (sterilization filtration step).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.