Patent · US Active

Ligands to cereblon (CRBN)

US12110292B2 · kind B2 · utility

0Cited by

2References

16Claims

0Family size

Assignee

DANA-FARBER CANCER INSTITUTE, INC. · US

Inventors

Nathanael S. Gray · Boston, US
Tinghu Zhang · Brookline, US
Eric Fischer · East Sharon, US
Zhixiang He · Brookline, US
Guangyan Du · Brookline, US
Katherine Donovan · Boston, US
Radoslaw Nowak · Boston, US
Jing Yuan · Lansdale, US

Key dates

Filing date	Nov 11, 2022
Grant date	Oct 8, 2024
Priority date	—
Expiry date	Nov 11, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D473/34
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed are compounds with immunomodulatory activity, methods of making the compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat diseases or disorders characterized or mediated by dysfunctional protein activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.