Method of manufacturing a recombinant polypeptide
US12116559B2 · kind B2 · utility
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4References
6Claims
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Key dates
| Filing date | Dec 22, 2021 |
| Grant date | Oct 15, 2024 |
| Priority date | — |
| Expiry date | Dec 22, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/15051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
We have modified a commercially-available adherent cell culture bioreactor in several ways to increase productivity of cultured cells, while decreasing contamination risk. We found that modifying a commercially-available adherent cell culture bioreactor to provide for slower cell culture medium flow unexpectedly and dramatically increases the productivity of the cultured adherent cells. We also developed a new sampling manifold configuration and new way of taking samples, to reduce contamination risk.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.