Autophagy as a therapeutic target for intracranial aneurysm
US12116597B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 25, 2022 |
| Grant date | Oct 15, 2024 |
| Priority date | — |
| Expiry date | May 25, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed here are uses of autophagy inhibitors for treating a subject at risk of suffering from an aneurysm. The present disclosure demonstrates that autophagy plays a role in THSD1-mediated focal adhesion stability and aneurysm formation and characterizes molecular targets for therapeutic intervention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.