Method for the production of domain antibodies
US12116607B2 · kind B2 · utility
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3References
17Claims
0Family size
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Key dates
| Filing date | Sep 1, 2016 |
| Grant date | Oct 15, 2024 |
| Priority date | — |
| Expiry date | Sep 18, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/626
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for producing a domain antibody in a yeast, wherein the formation of disulfide bridges in the domain antibody is promoted. The method encompasses the addition of oxidizing agents, preferably oxidizing metal ions, preferably one or more selected from Cu2+, Fe2+, Fe3+ and Zn2+.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.