Early detection marker for degenerative osteoarthritis with TRIM24-RIP3 axis
US12117455B2 · kind B2 · utility
0Cited by
0References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 15, 2021 |
| Grant date | Oct 15, 2024 |
| Priority date | — |
| Expiry date | Aug 27, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/105
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is the novel use of TRIM24 and RIP3 as biomarkers for diagnosing osteoarthritis, in which it is first identified that TRIM24 and RIP3 can be used as biomarkers for diagnosing osteoarthritis by confirming the tendency of TRIM24 expression to decrease and RIP3 expression to increase at the onset of osteoarthritis. These two proteins are useful in confirming the change in the expression level from the onset of osteoarthritis, thus enabling early diagnosis of osteoarthritis and effectively blocking the progression of osteoarthritis at an early stage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.