Compositions and methods for targeted delivery to cells
US12121610B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 2023 |
| Grant date | Oct 22, 2024 |
| Priority date | — |
| Expiry date | May 3, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compositions, kits, and methods for potent delivery to a cell of a subject. The cell can be of a particular cell type, such as a basal cell, a ciliated cell, or a secretory cell. In some cases, the cell can be a lung cell of a particular cell type. Also described herein are pharmaceutical compositions comprising a therapeutic or prophylactic agent assembled to a lipid composition. The lipid composition can comprise an ionizable cationic lipid, a phospholipid, and a selective organ targeting lipid. Further described herein are high-potency dosage forms of a therapeutic or prophylactic agent formulated with a lipid composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.