Crosslinked polysaccharide based absorbents for removal of anti-A and/or anti-B antibodies from human plasma and whole blood
US12121879B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 2019 |
| Grant date | Oct 22, 2024 |
| Priority date | — |
| Expiry date | Dec 6, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/80
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.