Patent · US Active

Method for separating flavokawain and kavalactone, kavalactone, and microencapsulated kavalactone

US12122744B1 · kind B1 · utility

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6Claims
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Assignee

Inventors

Key dates

Filing dateMar 7, 2024
Grant dateOct 22, 2024
Priority date
Expiry dateMar 7, 2044

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/54
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

The present application relates to a technical field of separating kavalactone and flavokawain, and in particular, to a method for separating flavokawain and kavalactone, kavalactone, and microencapsulated kavalactone. The separation method includes: S1. grinding root of piper methysticum, extracting by supercritical carbon dioxide and collecting a residue for later use, in which an extraction temperature is 45-50° C. and an extraction pressure is 4-8 MPa; S2. extracting the residue by supercritical carbon dioxide, and collecting extracted oil for later use, in which an extraction temperature is 60-80° C. and an extraction pressure is 20-50 MPa; S3. performing re-extraction and adsorption on the extracted oil to obtain a primary product of the kavalactone; and S4. crystallizing the primary product of kavalactone to obtain the kavalactone. The obtained kavalactone is used for microencapsulated kavalactone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.