Patent · US Active

Composition for preventing or treating cognitive dysfunction including inhibitor or MECP2 expression

US12122999B2 · kind B2 · utility

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3Claims
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Assignee

Inventors

Key dates

Filing dateMay 16, 2022
Grant dateOct 22, 2024
Priority date
Expiry dateMay 29, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/531
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed is a composition for preventing or treating a degenerative brain disease. The composition includes, as an active ingredient, a MECP2 inhibitor for treating the degenerative brain disease, a polynucleotide encoding the MECP2 inhibitor or a recombinant virus containing the MECP2 inhibitor. The composition is useful for the treatment of a degenerative brain disease (particularly Alzheimer's syndrome) caused by beta-amyloid. In addition, the composition is effective in improving or ameliorating deterioration of cognitive functions and social deficits caused by Alzheimer's syndrome.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.