Composition for preventing or treating cognitive dysfunction including inhibitor or MECP2 expression
US12122999B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 16, 2022 |
| Grant date | Oct 22, 2024 |
| Priority date | — |
| Expiry date | May 29, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/531
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a composition for preventing or treating a degenerative brain disease. The composition includes, as an active ingredient, a MECP2 inhibitor for treating the degenerative brain disease, a polynucleotide encoding the MECP2 inhibitor or a recombinant virus containing the MECP2 inhibitor. The composition is useful for the treatment of a degenerative brain disease (particularly Alzheimer's syndrome) caused by beta-amyloid. In addition, the composition is effective in improving or ameliorating deterioration of cognitive functions and social deficits caused by Alzheimer's syndrome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.