Methods, systems, and apparatuses for tissue ablation using a modulated exponential decay pulse

US12127779B2 · kind B2 · utility

Assignee

• INTERSCIENCE · US

Inventors

• Enric Günther · Hattersheim, DE
• Boris Rubinsky · Givatayim, IL
• Nina Klein · Friedrichsdorf, DE
• Paul Mikus · Irvine, US
• Michael Klaus Stehling · Rödermark, DE

Key dates

• Filing date: Sep 4, 2019
• Grant date: Oct 29, 2024
• Expiry date: Oct 9, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/325
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Example methods and apparatuses are disclosed for providing tissue ablation through electrolysis, electroporation, or a combination thereof. A pulse that has an element of decay may be applied to a target for tissue ablation while the decay is modulated. In some examples, apparatus including a controller and switches may be used to modulate the decay and/or selectively apply the pulse to the target. The apparatus may further include resistors and/or other elements to modulate a magnitude of the pulse and/or a slope of a decay of the pulse.