Composition comprising probiotics and polypeptide having binding affinity for IgE and use thereof
US12128076B2 · kind B2 · utility
1Cited by
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6Claims
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Key dates
| Filing date | Jan 14, 2019 |
| Grant date | Oct 29, 2024 |
| Priority date | — |
| Expiry date | Sep 20, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition containing, as active ingredients, probiotics and a polypeptide with a binding ability to IgE is disclosed. In particular, a synergistic effect of remarkably decreasing food allergy was identified at the time of combined administration of probiotics and a recombinant protein containing an extracellular domain of an alpha subunit of an IgE Fc receptor. Therefore, it is expected that the composition is highly industrially applicable due to being able to exhibit a remarkable therapeutic effect on an IgE-mediated allergic disease as compared with conventional pharmaceutical compositions.
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