ASGPR-binding compounds for the degradation of extracellular proteins
US12128106B2 · kind B2 · utility
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Key dates
| Filing date | Feb 22, 2024 |
| Grant date | Oct 29, 2024 |
| Priority date | — |
| Expiry date | Feb 22, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/95
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.