Oral mucosal electroporation device and use thereof
US12128229B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 8, 2021 |
| Grant date | Oct 29, 2024 |
| Priority date | — |
| Expiry date | Mar 30, 2041 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A device for electroporating cells of a mammalian mucosal membrane includes a housing, an electrode microneedle plate, a voltage return electrode coupled to the housing, and an energy source. The energy source is configured to generate and deliver through the electrode microneedle plate and the voltage return electrode at least one pulse of electrical energy having an electric potential sufficient to electroporate the cells. The electrode microneedle plate is configured to provide an even distribution of a pharmaceutical formulation from the housing and to the mucosal membrane. The electrode microneedle plate includes a plurality of microneedles that are configured to contact the mucosal membrane, deliver the pharmaceutical formulation to a specific depth, and deliver the at least one pulse of ergy to the cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.