Difluoro phenyl amide RIP1 inhibitor
US12129221B2 · kind B2 · utility
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4Claims
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Assignee
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Key dates
| Filing date | May 19, 2021 |
| Grant date | Oct 29, 2024 |
| Priority date | — |
| Expiry date | May 12, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The disclosed compounds inhibit cellular necrosis, and include corresponding sulfonamides, prodrugs and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.