Modulators of Mas-related G-protein receptor X2 and related products and methods
US12129243B2 · kind B2 · utility
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Key dates
| Filing date | Nov 17, 2023 |
| Grant date | Oct 29, 2024 |
| Priority date | — |
| Expiry date | Dec 8, 2043 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods are provided for modulating MRGPRX2 generally, or for treating a MRGPRX2 or a MRGPRX2 ortholog dependent condition, more specifically, by contacting the MRGPRX2 or the MRGPRX2 ortholog by administering to a subject in need thereof, respectively, an effective amount of a compound having structure (I): or a pharmaceutically acceptable salt, isomer, hydrate, solvate or isotope thereof, wherein W, Z, R1, R2, R3, R4, R5, R6 and Rx are as defined herein. Pharmaceutical compositions containing such compounds, as well as the compounds themselves, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.