Engineered adenosine deaminases and base editors thereof
US12129478B1 · kind B1 · utility
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Key dates
| Filing date | Aug 28, 2023 |
| Grant date | Oct 29, 2024 |
| Priority date | — |
| Expiry date | Aug 28, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/107
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are adenosine deaminases, base editors comprising the adenosine deaminases and complexes comprising the base editors. The adenosine deaminases and the base editors exhibited superior adenine editing effects and achieved A·T base pair to G·C base pair transformation at DNA level.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.