Methods of substituting pathogenic amino acids using programmable base editor systems
US12133884B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | May 11, 2019 |
| Grant date | Nov 5, 2024 |
| Priority date | — |
| Expiry date | Jan 29, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions and methods of using base editors comprising a polynucleotide programmable nucleotide binding domain and a nucleobase editing domain in conjunction with a guide polynucleotide. Also provided herein are base editor systems for editing nucleobases of target nucleotide sequences.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.