Patent · US Active

Microbubble-extracellular vesicle complexes

US12133891B2 · kind B2 · utility

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Key dates

Filing dateNov 2, 2021
Grant dateNov 5, 2024
Priority date
Expiry dateMar 2, 2042

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61N2007/0078
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed herein are a microbubble-extracellular vesicle complex, a production method therefor, and a system for driving the same. In one aspect, preferred microbubble-extracellular vesicle complexes may comprise an ultrasound contrast agent-based microbubble, an extracellular cell derived from a natural killer cell (NK cell), a human glial cell, or a human mesenchymal stem cell, and a coupling medium and can be derive in a 3D mode using ultrasonic waves and deliver a drug loaded in the extracellular vesicle to a target site.

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