IL-15Rα sushi domain—IL-15 fusion proteins
US12134639B2 · kind B2 · utility
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9References
16Claims
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Key dates
| Filing date | Jun 13, 2019 |
| Grant date | Nov 5, 2024 |
| Priority date | — |
| Expiry date | Jun 13, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the stimulation of the IL-15Rbeta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells. Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.