Method for increasing the yield of oxidosqualene, triterpenes and/or triterpenoids and host cell therefore

US12134787B2 · kind B2 · utility

Assignees

• Fraunhofer-Gesellschaft zur förderung der angewandten Forschung e.V. · DE
• WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER · DE

Inventors

• Christian Schulze Gronover · Kohlenbissen, DE
• Lowis Gerrit Boje Mueller · Rheine, DE
• Nicole Van Deenen · Kohlenbissen, DE
• Jan Niklas Broeker · Kohlenbissen, DE

Key dates

• Filing date: Apr 8, 2019
• Grant date: Nov 5, 2024
• Expiry date: Dec 1, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2500/20
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a method of increasing the yield of at least one of oxidosqualene, triterpenes and/or triterpenoids in a specifically engineered host cell and a respective host cell as well as to the use of said host cell for manufacturing the at least one of oxidosqualene, triterpenes and/or triterpenoids.