Patent · US Active

In-vitro method for determining a cell type of a white blood cell without labeling

US12135322B2 · kind B2 · utility

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14Claims

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Assignee

Siemens Healthineers AG · DE

Inventors

Lukas Richter · Hirschaid, DE
Oliver Hayden · Moosburg an der Isar, DE
Matthias Ugele · Dresden, DE
Markus Weniger · Nuremberg, DE
Oliver Schmidt · Erlangen, DE
Manfred Stanzel · Erlangen, DE

Key dates

Filing date	Mar 11, 2019
Grant date	Nov 5, 2024
Priority date	—
Expiry date	Jan 23, 2042

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/30024
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

An in-vitro method for determining a cell type of a white blood cell in a biological sample does so without labeling, wherein a microscopy apparatus images the cell, and physical parameters of the cell are ascertained from the image of the cell by an automated image analysis. The cell type of the white blood cell is determined on the basis of the physical parameters and on the basis of principal component analysis parameters (PCA parameters) , wherein the principal component analysis parameters comprise linear combinations of at least some of the physical parameters.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.