Patent · US Active

Serially deposited biomolecules

US12135323B1 · kind B1 · utility

0Cited by
56References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 9, 2020
Grant dateNov 5, 2024
Priority date
Expiry dateSep 11, 2041

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/5438
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Disclosed herein is a multiplex microarray having serially attached non-functionalized biomolecules attached to a polymer coating covering each electrode of an array of electrodes for assays and a method of making the multiplex microarray. The method comprises serially blocking the electrodes of the microarray with a blocking protein, electropolymerizing pyrrole or a functionalized pyrrole on the electrodes where the biomolecule is not present during polymerization, exposing the microarray to a biomolecular solution containing a non-functionalized biomolecule for attachment to the polymer coating, and then repeating the steps to form the multiplex microarray.

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