Patent · US Active

Multikinase inhibitors of VEGF and TGF beta and uses thereof

US12138252B2 · kind B2 · utility

0Cited by
3References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 29, 2020
Grant dateNov 12, 2024
Priority date
Expiry dateMay 9, 2043

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P29/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pharmaceutical composition for prevention or treatment of a disease or disorder characterized by chronic inflammation, with associated angiogenesis and fibrosis, wherein the disease or disorder is selected from the group consisting of rosacea, psoriasis, erythema multiforme, bullous pemphigoid, hereditary hemorrhagic telangiectasia, rheumatoid arthritis, atopic dermatitis, and dermal wound healing. The pharmaceutical composition includes at least one multi-kinase inhibitor selected from the group consisting of axitinib, nintedanib, and lenvatinib.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.