Patent · US Active

Cell-penetrating peptides for antisense delivery

US12138312B2 · kind B2 · utility

0Cited by

0References

19Claims

0Family size

Assignees

Sarepta Therapeutics, Inc. · US
Massachusetts Institute of Technology · US

Inventors

Justin Wolfe · Lawrenceville, US
Colin M. Fadzen · Cambridge, US
Zi-Ning Choo · Cambridge, US
Rebecca L. Holden · Cambridge, US
Monica Yao · Cambridge, US
Gunnar J. Hanson · Cambridge, US
Bradley L. Pentelute · Cambridge, US

Key dates

Filing date	Oct 17, 2018
Grant date	Nov 12, 2024
Priority date	—
Expiry date	Oct 2, 2040

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are oligonucleotides, cell penetrating peptides, and peptide-oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides, peptides, and peptide-oligonucleotide-conjugates described herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.