Increased bioavailability of transdermally delivered agents
US12138415B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 13, 2020 |
| Grant date | Nov 12, 2024 |
| Priority date | — |
| Expiry date | Jul 24, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2037/0061
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for delivering a bioactive agent to the cardiovascular system is described. The method delivers the agent at a high bioavailability and with little loss of agent to the natural defense mechanisms of the body. For instance, little or none of the bioactive agent will be sequestered in lymph tissue and prevented from circulation in the cardiovascular system. The method includes utilization of a transdermal delivery device including microneedles with structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.