Methods and compositions for decreasing soluble immune receptor CD28
US12139534B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Mar 14, 2019 |
| Grant date | Nov 12, 2024 |
| Priority date | — |
| Expiry date | Feb 23, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of treating cancer and improving immunotherapies comprising decreasing soluble immune receptor levels are provided. Agents that bind membranal immune receptor and inhibit proteolytic cleavage of the receptor and agents that bind soluble immune receptor and that are neither receptor agonists nor antagonists are also provided, as are methods of producing these agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.