Patent · US Active

Mir-17˜92 as therapeutic or diagnostic target of motor neuron (MN) degeneration diseases

US12144822B2 · kind B2 · utility

0Cited by

2References

8Claims

0Family size

Assignee

ACADEMIA SINICA · TW

Inventors

Jun Chen · San Jose, US
Kuan-Chih Peng · Taipei, TW
Ying-Tsen Tung · Taipei, TW

Key dates

Filing date	Apr 2, 2019
Grant date	Nov 19, 2024
Priority date	—
Expiry date	Nov 20, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/178
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates to mir-17˜92 as a candidate therapeutic or diagnostic target of motor neuron (MN) degeneration diseases. Expression of mir-17˜92 is sustained throughout adulthood in spinal MNs and specifically decreases before the onset of MN loss in SOD1G93A mice. Accordingly, mir-17˜92 can be used as a candidate therapeutic target for ALS.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.