Arginine depletion therapy for treatment of GAMT deficiency
US12144848B2 · kind B2 · utility
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12References
35Claims
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Key dates
| Filing date | Oct 18, 2019 |
| Grant date | Nov 19, 2024 |
| Priority date | — |
| Expiry date | Jan 16, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y305/03006
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions therefor of treating GAMT deficiency or guanidino acetate (GAA) toxicity in a subject comprising administration of an arginine depleting enzyme. An therapeutic formulation can include an arginase, an arginine deiminase or a combination thereof and optionally other compounds, and can be adapted for intravenous or subcutaneous administration to a subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.