PDX1 pancreatic endoderm cells in cell delivery devices and methods thereof
US12144908B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 2, 2023 |
| Grant date | Nov 19, 2024 |
| Priority date | — |
| Expiry date | Mar 2, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2535/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are cell encapsulation devices and methods for transplanting cells, such as pancreatic endoderm cells, into a host. In some examples, a cell encapsulation can comprise a lumen configured to receive cells therein, a cell-excluding membrane, where the lumen is internal to the cell-excluding membrane, and a non-woven fabric layer external to the cell-excluding membrane, where the non-woven fabric layer and the cell-excluding membrane comprise perforations. The device can further comprise a woven mesh external to the non-woven fabric layer, where the non-woven fabric layer provides protection to the cell-excluding membrane from direct contact with the woven mesh.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.