Microfluidic devices and methods for delivering solutions to biological material
US12145150B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | May 8, 2023 |
| Grant date | Nov 19, 2024 |
| Priority date | — |
| Expiry date | May 18, 2043 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/06
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.