Patent · US Active

Thiophosphorodichloridate reagents for chemoselective histidine bioconjugation

US12145964B2 · kind B2 · utility

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15Claims

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Assignee

The Regents of the University of California · US

Inventors

Christopher J. Chang · Berkeley, US
Shang Jia · Berkeley, US

Key dates

Filing date	Mar 20, 2021
Grant date	Nov 19, 2024
Priority date	—
Expiry date	Sep 2, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/21
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Proteins are labeled by contacting the protein with a thiophosphorodichloridate reagent under conditions to effect chemoselective histidine conjugation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.