Use of microRNA (miRNA) marker in preparation of product for evaluating therapeutic effect of olanzapine in treatment of schizophrenia (SZ) and kit
US12146192B2 · kind B2 · utility
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Key dates
| Filing date | Aug 4, 2021 |
| Grant date | Nov 19, 2024 |
| Priority date | — |
| Expiry date | Aug 4, 2041 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A use of a detection reagent for a microRNA (miRNA) marker miR-143-3p in the preparation of a product for evaluating a therapeutic effect of olanzapine in the treatment of schizophrenia (SZ) and a kit are provided. An expression level of miR-143-3p can be detected to determine a therapeutic effect of olanzapine in the treatment of SZ of a patient, and can be used as a detection or treatment index in clinical practice, which provides a theoretical basis for the mechanism research of SZ and the clinical application.
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