Patent · US Active

C-RAF mutants that confer resistance to RAF inhibitors

US12146196B2 · kind B2 · utility

0Cited by

2References

8Claims

0Family size

Assignee

DANA-FARBER CANCER INSTITUTE, INC. · US

Inventors

Caroline Emery · Brookline, US
Rajee Antony · Norwood, US
Levi A. Garraway · Newton, US

Key dates

Filing date	Sep 11, 2023
Grant date	Nov 19, 2024
Priority date	—
Expiry date	Sep 11, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/11001
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nucleic acids and proteins having a mutant C-RAF sequence, and methods of identifying patients having cancer who are likely to benefit from a combination therapy and methods of treatment are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.