System and methods for sealing a channel in tissue

US12150632B2 · kind B2 · utility

Assignee

• The Provost, Fellows, Scholars and Other Members of Board of Trinity College Dublin · IE

Inventors

• Garrett Ryan · Sydney, AU
• Colm McGarvey · Dublin, IE

Key dates

• Filing date: Jun 27, 2022
• Grant date: Nov 26, 2024
• Expiry date: Oct 17, 2042

Classification

• Technology area (CPC —): General

Abstract

A system for performing a minimally invasive percutaneous procedure comprises a medical device comprising a hydrogel delivery needle (4) with a tip and a hydrogel outlet (6), an injectable, shear-thinning, self-healing viscoelastic hydrogel that exhibits a storage modulus (G′) of at least 600 Pa, and a tan δ (G″/G′) from 0.1 to 0.6 in dynamic viscoelasticity measured by a rheometer at 1 Hz and 1% strain rate at 25° C. The system may also comprise a coaxial cannula (2) having a lumen configured for receipt of the hydrogel delivery needle (4), wherein the hydrogel delivery needle comprises an adjustable positioning mechanism (8) configured to limit the advancement depth of the hydrogel delivery needle through the coaxial cannula to a predetermined depth distal to a distal-most end of the coaxial cannula.