Patent · US Active

Formulations of PBMCs

US12150982B2 · kind B2 · utility

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18Claims
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Assignee

Inventors

Key dates

Filing dateDec 28, 2021
Grant dateNov 26, 2024
Priority date
Expiry dateDec 28, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2710/20034
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present application provides formulations of modified peripheral blood mononuclear cells (PBMCs), wherein the formulation comprises: PBMCs comprising at least one antigen (e.g., a human papillomavirus (HPV) antigen) and a cryopreservation medium. In some embodiments, the PBMCs are conditioned by incubating the PBMC in the presence of an adjuvant.

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