Drug delivery systems comprising solid solutions of weakly basic drugs
US12151028B2 · kind B2 · utility
0Cited by
6References
18Claims
0Family size
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Key dates
| Filing date | Nov 2, 2020 |
| Grant date | Nov 26, 2024 |
| Priority date | — |
| Expiry date | May 18, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 μg/mL at pH 6.8.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.