Patent · US Active

T cell receptor for identifying AFP antigen

US12152065B2 · kind B2 · utility

0Cited by

1References

26Claims

0Family size

Assignee

XLIFESC, LTD. · CN

Inventors

Yi Li · Shanghai, CN
Jing-Shan Hu · Hefei, CN
Jun Li · Greenville, US
Hanli SUN · Longbeilingcun, CN

Key dates

Filing date	Jul 29, 2019
Grant date	Nov 26, 2024
Priority date	—
Expiry date	Mar 29, 2042

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/16043
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A T cell receptor (TCR) capable of specifically binding to a short peptide FMNKFIYEI derived from an AFP antigen. The antigen short peptide FMNKFIYEI can form a complex with HLA A0201 and be presented together with same to the cell surface. A nucleic acid molecule encoding the TCR, a vector comprising the nucleic acid molecule, and a cell that transduces the TCR.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.