Patent · US Active

Method for preparing microcarrier suitable for three-dimensional cell culture and reaction apparatus

US12152249B2 · kind B2 · utility

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1References
12Claims
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Assignee

Inventors

Key dates

Filing dateOct 15, 2020
Grant dateNov 26, 2024
Priority date
Expiry dateJan 11, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/74
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Provided herein is a method for preparing microcarrier particles, comprising the steps of allowing the dispersed phase liquid flow through a multi-hole plate at a low temperature to form liquid microspheres in a continuous phase, and enabling a synthetic polymer and/or natural biological macromolecules within the liquid microspheres to be subject to a curing reaction at a low temperature to form particles. Further provided herein are the method for preparing an emulsion and an apparatus and process system for preparing microcarrier particles, which can be used for preparing emulsions and microcarrier particles on a large scale.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.