Patent · US Active

TAL-Tet1 fusion proteins and methods of use thereof

US12152254B2 · kind B2 · utility

0Cited by
25References
9Claims
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Inventors

Key dates

Filing dateJan 14, 2021
Grant dateNov 26, 2024
Priority date—
Expiry dateAug 31, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/81
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array or zinc finger, and a catalytic domain comprising a sequence that catalyzes hydroxylation of methylated cytosines in DNA, and methods of use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.