Transaminase mutant and use thereof
US12152263B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | May 30, 2019 |
| Grant date | Nov 26, 2024 |
| Priority date | — |
| Expiry date | Oct 14, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y206/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are a transaminase mutant and a method for producing a chiral amine using the same. An amino acid sequence of the transaminase mutant is an amino acid sequence obtained by mutation occurred in an amino acid sequence as shown in SEQ ID NO: 1, and the mutation includes at least one of the following mutation sites: position 3, position 5, position 8, position 25, position 32, position 45, position 56, position 59, position 60, position 84, position 86, position 164, position 176, position 178, position 180, position 187, position 197, position 206, position 207, position 242, position 245, position 319 and position 324.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.