Patent · US Active

3D oscillating gradient-prepared gradient spin-echo imaging method, and device

US12153114B2 · kind B2 · utility

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Key dates

Filing dateSep 26, 2022
Grant dateNov 26, 2024
Priority date
Expiry dateOct 2, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01R33/56341
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for 3D oscillating-gradient prepared gradient spin-echo imaging and a device. The imaging method comprises the following steps: first, using a global saturation module to destroy previous residual transverse magnetization; second, embedding a pair of trapezoidal cosine oscillating gradients into a 90°x-180°y-90°−x radiofrequency pulse by a diffusion encoding module, to separate diffusion encoding from signal acquisition; then, using a fat saturation module to suppress a fat signal; finally, acquiring a signal by means of gradient spin-echo readout, and correcting phase errors among multiple excitations by multiplexed sensitivity-encoding reconstruction. Compared with a 2D plane echo-based oscillating gradient diffusion sequence used on a 3T clinical system, a 3D oscillating-gradient prepared gradient spin-echo sequence effectively reduces the imaging time, improves the signal to noise ratio, and is beneficial to clinical transformation of time-dependent diffusion MRI technology.

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