Hydrogel patch including additive solution adjustable for its syneresis pattern and method of manufacturing the composition
US12156923B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 25, 2021 |
| Grant date | Dec 3, 2024 |
| Priority date | — |
| Expiry date | Jul 19, 2043 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/594
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are a hydrogel patch, which controls syneresis of a hydrogel so as to enhance transdermal delivery of an active ingredient and has good physical properties, and a preparation method therefor. The hydrogel patch contains: a hydrogel composed of a mixture of phase A consisting of a crosslinking agent and purified water, phase B consisting of an organic polymer and a polyhydric alcohol, and phase C consisting of a pH adjusting agent and purified water; and a filling solution composed of a mixture of phase D consisting of a humectant and purified water, phase E consisting of a thickener and a polyhydric alcohol, and phase F consisting of a pH adjusting agent and purified water. The hydrogel of composition A is filled with the filling solution of composition C, and the hydrogel of composition B is filled with the filling solution of composition D.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.