Macrocyclic inhibitors of ALK, TRKA, TRKB, and ROS1
US12157738B2 · kind B2 · utility
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37Claims
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Key dates
| Filing date | Sep 26, 2019 |
| Grant date | Dec 3, 2024 |
| Priority date | — |
| Expiry date | Dec 9, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds of formula (I) or (II): that inhibit ALK, TRKA, TRKB, TRKC and ROS1. Also disclosed are pharmaceutical compositions containing the compounds and methods of using the compounds to treat disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.