Patent · US Active

MAGE-A4 peptide dual T cell engagers

US12161673B2 · kind B2 · utility

0Cited by
12References
40Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 13, 2023
Grant dateDec 10, 2024
Priority date
Expiry dateSep 13, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described herein are antigen binding proteins with specificity to Melanoma-Associated Antigen A4 (MAGE-A4) peptide-MHC (pMHC). Also described are multispecific antigen binding proteins comprising an antigen binding domain with specificity to CD3, and at least one MAGE-A4 pMHC antigen binding domain. Methods of treating cancer with the same are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.