F-18 labeled chiral pure derivative of hydroxyfuran, preparation method and use thereof
US12162811B2 · kind B2 · utility
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Key dates
| Filing date | May 25, 2023 |
| Grant date | Dec 10, 2024 |
| Priority date | — |
| Expiry date | May 25, 2043 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An F-18 labeled chiral pure derivative of hydroxyfuran, a preparation method and use thereof were provided. (4R, 5R)[18F]FAA provided by the present disclosure is a chiral pure radioactive compound, and three other chiral pure [18F]FAA structural formulae are also provided by the present disclosure. The present disclosure provides a chiral pure radioactive probe (4R, 5R)[18F]FAA, which shows unique tumor diagnostic efficiency and similar distribution to AA, and can be used for early diagnosis of tumors, pathological studies, assessment of disease progression, and evaluation for efficacy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.