Enhanced antigen presenting ability of RNA car T cells by co-introduction of costimulatory molecules
US12162922B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Apr 22, 2021 |
| Grant date | Dec 10, 2024 |
| Priority date | — |
| Expiry date | Apr 11, 2042 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides T cells comprising nucleic acid sequence encoding a chimeric antigen receptor and a nucleic acid sequence encoding an enhancer of T cell priming, compositions including the T cells, and methods of using the T cells to treat diseases associated with the expression of disease-associated antigens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.