Anti-idiotypic antibodies against anti-KLK2 antibodies

US12162951B2 · kind B2 · utility

Assignee

• JANSSEN BIOTECH, INC. · US

Inventors

• Zemeda Ainekulu · San Diego, US
• Qiang Chen · Sollentuna, SE
• Ellen Chi · San Diego, US
• Wilson Edwards · Encinitas, US
• Matt Husovsky · Ramona, US
• Ann Lacombe · San Diego, US
• Quynh Nguyen · San Diego, US
• Paul H. Kim · Del Mar, US
• H. Mimi Zhou · San Diego, US
• John Lee · Philadelphia, US

Key dates

• Filing date: Jul 15, 2021
• Grant date: Dec 10, 2024
• Expiry date: Jul 15, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/96455
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a KL2B413 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include KL2B413.