Use of miR-132 and miR-212 in preparation of drug for treating addiction
US12163133B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Jan 19, 2021 |
| Grant date | Dec 10, 2024 |
| Priority date | — |
| Expiry date | Oct 14, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/531
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure provides a non-therapeutic method for regulating DAT gene expression in a cell, which includes the step of increasing or decreasing an amount of a miR-132/212 in the cell; further provides a use of the above miRNA, an enhancer thereof or an attenuator thereof in preparing a drug for regulating uptake of dopamine by a cell; and an application of the above miRNA, the enhancer thereof or the attenuator thereof in preparing a drug for treating psychoactive substance addiction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.