Quality control methods for automated cell processing
US12163146B2 · kind B2 · utility
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46References
23Claims
0Family size
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Key dates
| Filing date | Nov 10, 2020 |
| Grant date | Dec 10, 2024 |
| Priority date | — |
| Expiry date | Nov 7, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides methods for assessing and optimizing cellular quality of a cell-based therapy that is being produced in an automated cell engineering system. The methods suitably include monitoring molecular characteristics of the cells before, during, and after the automated process to provide feedback to the process parameters. In embodiments, the cells being produced are Chimeric Antigen Receptor (CAR) T-cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.